Paliperidone palmitate - Names and Identifiers
Name | Paliperidone Palmitate
|
Synonyms | RO92670 RO 92670 UNII-R8P8USM8FR Invega Sustenna Paliperidone palmitate Paliperidone Palmitate Paliperidone Palmitate [USAN] 9-Hydroxyrisperidone palmitate (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidin-9-yl hexadecanoate (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)et
hyl)-2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyriMi
din-9-yl hexadecanoate Hexadecanoic acid 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester Hexadecanoic acid 3-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]-ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester Hexadecanoic acid, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido(1,2-a)pyrimidin-9-yl ester
|
CAS | 199739-10-1
|
EINECS | 225-799-5 |
Paliperidone palmitate - Physico-chemical Properties
Molecular Formula | C39H57FN4O4
|
Molar Mass | 664.89 |
Density | 1.19 |
Melting Point | 110-115°C |
Boling Point | 736.3±70.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (Sl |
Appearance | Solid |
Color | Off-White to Light Beige |
pKa | 8.07±0.10(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Physical and Chemical Properties | |
Paliperidone palmitate - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 1.504 ml | 7.52 ml | 15.04 ml |
5 mM | 0.301 ml | 1.504 ml | 3.008 ml |
10 mM | 0.15 ml | 0.752 ml | 1.504 ml |
5 mM | 0.03 ml | 0.15 ml | 0.301 ml |
Last Update:2024-01-02 23:10:35
Paliperidone palmitate - Introduction
Paliperidone Palmitate (also known as PPP ester) is a chemical compound with the formula C32H64O2. It is a colorless to slightly yellow liquid with low toxicity and transparency, and is soluble in organic solvents such as alcohols and esters.
Paliperidone Palmitate are mainly used in industry as plasticizers and stabilizers. Plasticizers are chemical additives used to increase the softness and ductility of plastics. It is widely used in the manufacturing process of PVC (polyvinyl chloride) plastic, which can make the plastic easier to process, while improving its heat resistance and aging resistance. In addition, Paliperidone Palmitate can also be used in coatings, inks, adhesives and sealants.
The preparation method of Paliperidone Palmitate can be obtained by reacting palmitic acid with paliperidone. Palmitic acid is a common fatty acid that can be extracted from animal and vegetable oils or chemically synthesized. During the reaction, palmitic acid reacts with paliperidone under appropriate heating conditions to form a Paliperidone Palmitate.
Regarding the safety of Paliperidone Palmitate, it is considered to be a relatively safe compound. However, like all chemicals, attention is still paid to the relevant safe handling when used. When in contact with Paliperidone Palmitate, direct contact with skin and eyes should be avoided and appropriate protective gloves and glasses should be worn. At the same time, ensure that you operate in a well-ventilated environment and avoid inhaling its vapors.
In summary, Paliperidone Palmitate is a commonly used plasticizer and stabilizer used in plastics, coatings and adhesives. Its preparation method is simple, and safe operation needs to be observed during use.
Last Update:2024-04-10 22:29:15